Optophysiology Lab

led by Prof. Ilka Diester

Our Research

The ability to move is a fundamental feature of most animals which allows them to actively interact with our environment. We are investigating the underlying neural mechanisms and circuits of this ability. We do so with electrophysiological recordings and optogenetic manipulations combined with behavioral analysis. We look into the local processing of movement preparation and generation in the motor cortex as well as higher order structures, e.g. prefrontal cortex.

The goal is to create a better understanding of how neural subpopulations and pathways within and across brain areas influence motor behavior. In order to address these scientific aims we are constantly working on improving the existing techniques. We currently focus on the design of new optoelectronic probes and targeting strategies. Apart from advancing our basic knowledge about the neural mechanisms of movements, our results might help improving the design of new prosthetic devices and understanding of disorders in which the normal production of movements is disrupted.

Current News

New Article Published in bioRxiv

To study behavioral flexibility in freely-moving mice, we developed a versatile, low-cost, open-source behavioral setup, called FreiBox, allowing us to investigate the neuronal correlates of licking-based behavioral flexibility.

Dr. Artur Schneider is awarded two junior prizes for his doctoral thesis

The Bernstein-CorTec Award honors outstanding scientific achievements in the field of Computational Neuroscience and Neurotechnology. The Thomas Bayer Young Investigator Award recognizes outstanding theses in the field of data analysis and modeling in the life sciences. In 2022, both prizes are awarded to Dr. Artur Schneider for his Doctoral thesis.

Lab outing October, 2022

The way is arduous, but it is worth it: excursion to the castle ruins between Freiburg-St. Georgen and Ebringen.

Open Positions

IMBIT Opening
Make thinking visible
Research Unit 5159
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