Priv.-Doz. Dr. Philippe Coulon

Senior Research Scientist

Optophysiology - Optogenetics and Neurophysiology


University of Freiburg
Georges-Köhler-Allee 201
79110 Freiburg i. Br.

+49 (0)761 203-98637

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Focus of research

How do neuronal networks switch between states of activity in health and disease? The biological mechanisms that are fundamental to movement, naturally occurring sleep, attention, pain signalling, or the conscious awareness of our environment in the brain’s largest network, the thalamocortical system, can also be the cause for epilepsy, Parkinsonism, or autism spectrum disorders. Understanding these mechanisms is a crucial step to understanding the organisation, function, and dysfunction of the brain.


since 2018Venia legendi in Neurobiology, University Freiburg, Faculty of Biology (Privatdozent, Dr. rer. nat. habil.)
2017 - todayOptophysiology lab - Prof. Diester. Albert-Ludwigs-University Freiburg, Germany, Senior Research Scientist
2015 - 2016Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA, USA, Fellow PhD
2014Epilepsy Research Center Münster and Institute of Anatomy and Molecular Neurobiology, University Münster
10/2013Habilitation. Venia legendi in Physiology, Privatdozent, University Münster, Medical Faculty
2006 - 2013Institute of Physiology I, Münster (PostDoc 2006-2010, Senior PostDoc 2011-2012, Principal Investigator @ IMF Münster 2012-2013)
2005Coordinator of the International Graduate School of Neuro­science (IGSN), Bochum
01/2005Graduation as Dr. rer. nat. (PhD), Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany
2000 - 2005Research Associate, Institute of Neurobiology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany
11/2001Dipl.-Biol. (MSc Biology)
1994 - 2000Studied Biology, Dipl.-Biol. (MSc), Heinrich Heine University Düsseldorf, Germany


Book chapters

Coulon P (2021). Electrophysiological and Calcium Imaging Approaches to Study Metabotropic Glutamate Receptors. In: Olive M.F., Burrows B.T., Leyrer-Jackson J.M. (eds) Metabotropic Glutamate Receptor Technologies. Neuromethods, vol 164. Humana, New York, NY. DOI 10.1007/978-1-0716-1107-4.

Journal papers

Eriksson D, Schneck M, Schneider A, Coulon P & Diester I (2020). A starting kit for training and establishing in vivo electrophysiology, intracranial pharmacology, and optogenetics. J Neurosci Methods. 2020 Apr 15;336:108636. DOI: 10.1016/j.jneumeth.2020.108636.

Journal papers

Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P, Pape HC (2016). Short-term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. 2016 Oct 1;594(19):5695-710. DOI: 10.1113/JP271811.

Journal papers

Neyer C, Herr D, Kohmann D, Budde T, Pape HC, Coulon P. mGluR-mediated calcium signalling in the thalamic reticular nucleus (2016). Cell Calcium. 2016 Jun;59(6):312-23. DOI: 10.1016/j.ceca.2016.03.009.

Journal papers

Cerina M, Szkudlarek HJ, Coulon P, Meuth P, Kanyshkova T, Nguyen XV, Göbel K, Seidenbecher T, Meuth SG, Pape HC, Budde T (2015). Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing. Br J Pharmacol. 2015 Jun;172(12):3126-40. DOI: 10.1111/bph.13113.

Journal papers

Khodaie B, Lotfinia AA, Ahmadi M, Lotfinia M, Jafarian M, Karimzadeh F, Coulon P, Gorji A. Structural and functional effects of social isolation on the hippocampus of rats with traumatic brain injury (2015). Behav Brain Res. 2015 Feb 1;278:55-65. DOI: 10.1016/j.bbr.2014.09.034.

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